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Increase in lactate levels and decrease in glucose levels in the plasma and cerebrospinal fluid (CSF) were observed in mechanistic studies with SNAC in rats

Estos medicamentos tienen una advertencia importante (boxed warning) sobre el riesgo de tumores tiroideos de clulas C y estn contraindicados en pacientes con antecedentes personales o familiares de carcinoma medular de tiroides o sndrome de neoplasia endocrina mltiple tipo 2 (MEN2)

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GLP1R is expressed on beta cells in the pancreas

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